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Testimonial Tuesday - I am ASCPT: Lance Kuo-Esser and Yifan Zheng

By Lisa Infelise posted 2 days ago

  

Get to know ASCPT members @Lance Kuo-Esser and @Yifan Zheng!

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Lance Kuo-Esser, BS, Graduate Student, Cincinnati Children's, Cincinnati, Ohio, USA

What does being a 2026 Presidential Trainee Award Recipient mean to you?
It tells me that work at the intersection of pharmacometrics, clinical pharmacology, and translational decision-making is valued. I see it less as a finish line and more as confirmation that we are asking the right questions, with a responsibility to focus on work that is not just technically sound, but clinically useful.

Why did you submit your abstract for presentation at the ASCPT 2026 Annual Meeting?
I submitted my abstract to contribute to the broader conversation around pharmacoequity, particularly how quantitative approaches can help ensure patients are systematically under- or overtreated. ASCPT brings together people who care about both the methods and their clinical impact, and it felt like the right place to engage in that discussion.

What has been the greatest challenge in your career?
One of the biggest challenges has been translating technical work and models into something that can actually inform decisions. It is one thing to build a model, but another to communicate what it means, what the limitations are, and how it should or should not be used. That shift has shaped how I approach both modeling and collaboration.

Do you have a favorite tip or trick for clinical practice or research that you want to share?
While I am still new to the field, one thing that has stood out is that you cannot look at dose, exposure, response, or toxicity in isolation. Each piece matters, but the value comes from understanding how they fit together. I try to keep that full picture in mind and ask whether what we are proposing is not only effective but also realistic and tolerable in practice.

What is one thing people would be surprised to know about you?
Outside of research, I am involved in search and rescue and technical rescue operations. It is a very different environment, but it reinforces similar principles: making decisions with incomplete information, working under uncertainty, and prioritizing what matters most in real time. That mindset carries over directly into how I approach clinical pharmacology problems.

Lance has been a member of ASCPT since 2023.
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Yifan Zheng, PharmD, University of Michigan, Ann Arbor, MI

What does being a 2026 Presidential Trainee Award Recipient mean to you?
Receiving this award is both an honor and a meaningful recognition of my training in clinical pharmacology and translational research. It reflects my efforts to integrate clinical trial evidence to generate insights that are both mechanistically grounded and clinically actionable. It also represents the strong mentorship and collaborative environment that have shaped my development from the University of Michigan College of Pharmacy and my Merck Co-Op Education.

What professional accomplishment are you most proud of?
I am most proud of developing research that bridges clinical trial data and real-world evidence to inform treatment optimization. My work applies quantitative and causal modeling approaches to understand treatment response heterogeneity, with the goal of moving drug selection and individualized therapeutic strategies into routine clinical practice.

Who has inspired you in your career?
Mentors at Merck and Michigan have deeply inspired me in clinical pharmacology. My mentors emphasize the integration of quantitative rigor with clinical relevance and development. Their ability to translate trial-based evidence into real-world decision-making, while maintaining a strong pharmacologic foundation, has strongly influenced my research direction.

What has been the greatest challenge in your career?
One of the greatest challenges has been integrating evidence across domains, clinical trials, real-world data, and mechanistic pharmacology. Each source has distinct assumptions and limitations; aligning them into a coherent framework for inference and decision-making requires careful methodological and clinical consideration.

When you are not working, how do you spend your free time?
Outside of research, I enjoy singing, recording songs on social media, and participating in a cappella performances. It provides a creative outlet and a way to stay balanced while engaging with a collaborative community.

Dr. Zheng has been a member of ASCPT since 2025.
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